Dr Divya RajawatConsultant Psychiatrist · MBBS, MD Book evaluation
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Long-term careBlood monitoring required

Bipolar disorder and depression

Diagnosis, mood stabiliser management, and the blood monitoring these medicines require. Bipolar disorder is one of the most frequently misdiagnosed conditions in psychiatry — usually as depression alone.

Why it is so often missed

People seek help when they are low, not when they are high. The elevated periods feel like energy, productivity and confidence returning — so they are rarely reported, and a diagnosis of depression gets made on half the picture.

This matters because the treatments differ. An antidepressant given alone to someone with bipolar disorder can destabilise the mood rather than settle it — which is why the question about elevated periods is asked carefully, and asked of family too.

What people describe

People seek help for the lows and never mention the highs. That is how half of bipolar disorder gets treated as depression.

What people say

The second and third of these are the sentences that change a diagnosis.

I have been on antidepressants for six years. They work for a few months and then they do not.

Engineer, 38

There are weeks where I barely sleep and get an enormous amount done. I always thought that was the good part.

Designer, 29

My wife says I become a different person for a few weeks each year. I do not see it at the time.

Business owner, 44

Why it happens

Mood disorders are among the most clearly biological conditions in psychiatry, which is also why they respond so reliably to the right medication.

It runs strongly in families

Bipolar disorder has one of the highest heritabilities in medicine. A family history of bipolar disorder, of suicide, or of relatives described as having had a breakdown is one of the most useful pieces of information in the assessment.

Sleep is both symptom and trigger

Reduced need for sleep is one of the earliest signs of an episode starting, and sleep disruption — shift work, travel, a new baby — is one of the commonest triggers. This is why sleep is asked about so closely and protected so firmly.

What gets believed

Myth
Bipolar means dramatic mood swings through the day.
Actually
Day-to-day irritability is not bipolar disorder. The episodes are sustained — typically days to weeks of a clearly different state, noticeable to other people, not hour-to-hour shifts.
Myth
If medication is working, I can stop it.
Actually
This is the single commonest cause of relapse. Feeling well on a mood stabiliser is evidence that it is working, not that it is no longer needed. Stopping is sometimes right — but as a planned taper with monitoring, not a decision made alone in a good month.
Myth
The blood tests are just the doctor being cautious.
Actually
For lithium and valproate they are not optional. These medicines work within a narrow range and affect thyroid, kidney and liver function — the monitoring is what makes long-term use safe, and it is a reason to stay with one psychiatrist rather than drift between prescriptions.

Why continuous treatment matters

Bipolar disorder is manageable, and many people live entirely ordinary working lives with it. What determines how well it goes is largely consistency.

  • Each episode makes the next one more likely. Preventing episodes is the point of long-term treatment, not just ending the one in front of you.
  • The decisions made during a high are real. Money, jobs and relationships are affected by weeks that the person may not fully recall afterwards.
  • Getting the diagnosis right changes the medication entirely — which is why a second opinion is worth having if years of antidepressants have not held.

How it is assessed

01

A lifetime mood history

Not just how you feel now. The question is what the pattern has been across years — and specifically whether there have ever been sustained periods of the opposite.

02

Someone who knows you well

With your consent, a family member is often asked separately. Elevated periods are characteristically more visible from outside than from inside, and this single step changes a significant number of diagnoses.

03

Bloods before starting

Thyroid, kidney and liver function, and a pregnancy test where relevant. Several mood stabilisers are unsafe in pregnancy, and that conversation happens before prescribing rather than after.

What treatment involves

A mood stabiliser, chosen according to which pole dominates, what else is going on medically, and — for women of childbearing age — what is safe. Antidepressants are used cautiously and rarely alone.

Alongside the medication: a sleep routine that is protected rather than negotiable, early-warning signs written down while you are well, and a plan agreed in advance for what happens if they appear.

Monitoring is part of the treatment, not an extra

Lithium and valproate require regular blood levels and organ-function checks. If you are starting one of these, expect tests at defined intervals — this is what makes long-term use safe, and it is the reason to stay with one psychiatrist rather than move between prescribers.

First evaluation

Includes the written diagnosis and treatment plan. Reviews are ₹800.

₹1,200All inclusive

Questions

I was told I have depression. Could it be bipolar?

It is worth asking, particularly if antidepressants have worked briefly and then stopped, if you have had periods of unusually little sleep without tiredness, or if bipolar disorder runs in the family. That is exactly what a second opinion consultation is for.

Will I be on medication for life?

For bipolar disorder, long-term treatment is usually recommended, and that is said at the start rather than discovered later. The aim is the lowest effective dose with the fewest side effects, reviewed regularly — not a fixed prescription repeated indefinitely.

Can this be managed online?

The assessment and most reviews, yes. You will need local blood tests, and during an acute episode in-person care is usually safer. For a stable person on established medication, video review works well.

I am planning a pregnancy.

Tell us before, not after. Several mood stabilisers carry significant risks in pregnancy and the medication usually needs changing in advance. Stopping treatment abruptly carries its own risk, so this is planned rather than improvised.

Related areas of care

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